{"id":131687,"date":"2026-06-06T18:07:37","date_gmt":"2026-06-06T15:07:37","guid":{"rendered":"https:\/\/indexeconomic.com\/?p=131687"},"modified":"2026-06-06T18:07:37","modified_gmt":"2026-06-06T15:07:37","slug":"wegovy-pill-oral-semaglutide-recommended-by-chmp-for-approval-in-the-eu-as-the-first-oral-glp-1-representing-the-most-efficacious-oral-obesity-treatment-in-its-class","status":"publish","type":"post","link":"https:\/\/indexeconomic.com\/?p=131687","title":{"rendered":"Wegovy\u00ae pill (oral semaglutide) recommended by CHMP for approval in the EU as the first oral GLP-1 representing the most efficacious oral obesity treatment in its class"},"content":{"rendered":"<p style=\"text-align: left;\"><strong>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/strong><strong>With a mean weight loss of 16.6%[1], Wegovy\u00ae pill demonstrates best-in-class weight-loss efficacy and is the first oral GLP 1 treatment recommended by CHMP for weight management in the EU<\/strong><strong>.<\/strong><\/p>\n<p style=\"text-align: left;\"><strong>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/strong><strong>CHMP recommends Wegovy\u00ae pill for approval to reduce excess body weight and maintain long-term weight reduction. The recommendation also includes data from SELECT which demonstrates that Wegovy\u00ae reduces the risk of major adverse cardiovascular events (MACE)*, in the label<\/strong><\/p>\n<p style=\"text-align: left;\"><strong>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/strong><strong>Wegovy\u00ae pill is the only oral GLP-1 treatment with no drug-drug restrictions in the label<\/strong><\/p>\n<p style=\"text-align: left;\"><strong>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/strong><strong>Novo Nordisk plans to launch Wegovy\u00ae pill in select markets outside the US in the second half of 2026<\/strong><\/p>\n<p style=\"text-align: left;\">\n<p style=\"text-align: left;\">\u00a0Novo Nordisk today announced that the Committee for Medicinal Products for Human Use (CHMP) under the European Medicines Agency (EMA) has adopted a positive opinion, recommending marketing authorisation of Wegovy\u00ae pill (once-daily oral semaglutide 25 mg) to reduce excess body weight and maintain long-term weight reduction. The positive opinion also includes SELECT data in the label, demonstrating that Wegovy\u00ae reduces the risk of major adverse cardiovascular events (MACE)*<\/p>\n<p style=\"text-align: left;\">\n<p style=\"text-align: left;\">Wegovy\u00ae pill is the first oral glucagon-like peptide-1 (GLP-1) receptor agonist therapy recommended for approval by CHMP for weight management in the EU. The recommendation is based on the OASIS trial programme and the SELECT[2] trial. In the OASIS 4 trial, oral semaglutide 25 mg taken once daily demonstrated 16.6% mean weight loss when treatment was adhered to in adult participants with obesity or overweight with one or more comorbidities1. The weight loss achieved with Wegovy\u00ae pill is similar to that of injectable Wegovy\u00ae 2.4 mg. Furthermore, one in three people experienced 20% or greater weight loss in the OASIS 4 trial1<\/p>\n<p style=\"text-align: left;\">\n<p style=\"text-align: left;\">The well-known safety and tolerability profile of semaglutide was reaffirmed with Wegovy\u00ae pill in the OASIS 4 trial, which was comparable to previous semaglutide trials for weight management. Semaglutide is supported by more than 50 million patient-years of real-world safety data, and notably, the Wegovy\u00ae pill label includes no drug\u2013drug restrictions with concomitant medications<\/p>\n<p style=\"text-align: left;\">\n<p style=\"text-align: left;\">\u201cWe are encouraged by CHMP\u2019s positive opinion for Wegovy\u00ae pill, bringing the most efficacious oral GLP-1 in its class one step closer to becoming the first approved oral treatment in its class for weight management in the EU\u201d, said Mike Doustdar, president and CEO of Novo Nordisk. \u201cThe demand for effective and convenient obesity treatment is already evident in the U.S., where more than 1 million Americans began using Wegovy\u00ae pill within the first four months following launch. We look forward to bringing this innovative medicine to the first markets outside the US in the second half of 2026\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 With a mean weight loss of 16.6%[1], Wegovy\u00ae pill demonstrates best-in-class weight-loss efficacy and is the first oral GLP 1 treatment recommended by CHMP for weight management in the EU. \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 CHMP recommends Wegovy\u00ae pill for approval to reduce excess body weight and maintain long-term weight reduction. The recommendation also includes data from SELECT &hellip;<\/p>\n","protected":false},"author":2,"featured_media":131688,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[439],"tags":[],"class_list":["post-131687","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-english-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Wegovy\u00ae pill (oral semaglutide) recommended by CHMP for approval in the EU as the first oral GLP-1 representing the most efficacious oral obesity treatment in its class - \u0635\u062d\u064a\u0641\u0629 \u0627\u0644\u0645\u0624\u0634\u0631 \u0627\u0644\u0625\u0642\u062a\u0635\u0627\u062f\u064a<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/indexeconomic.com\/?p=131687\" \/>\n<meta property=\"og:locale\" content=\"ar_AR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Wegovy\u00ae pill (oral semaglutide) recommended by CHMP for approval in the EU as the first oral GLP-1 representing the most efficacious oral obesity treatment in its class - \u0635\u062d\u064a\u0641\u0629 \u0627\u0644\u0645\u0624\u0634\u0631 \u0627\u0644\u0625\u0642\u062a\u0635\u0627\u062f\u064a\" \/>\n<meta property=\"og:description\" content=\"\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 With a mean weight loss of 16.6%[1], Wegovy\u00ae pill demonstrates best-in-class weight-loss efficacy and is the first oral GLP 1 treatment recommended by CHMP for weight management in the EU. \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 CHMP recommends Wegovy\u00ae pill for approval to reduce excess body weight and maintain long-term weight reduction. The recommendation also includes data from SELECT &hellip;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/indexeconomic.com\/?p=131687\" \/>\n<meta property=\"og:site_name\" content=\"\u0635\u062d\u064a\u0641\u0629 \u0627\u0644\u0645\u0624\u0634\u0631 \u0627\u0644\u0625\u0642\u062a\u0635\u0627\u062f\u064a\" \/>\n<meta property=\"article:published_time\" content=\"2026-06-06T15:07:37+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/indexeconomic.com\/wp-content\/uploads\/2026\/06\/02-1-18.webp\" \/>\n\t<meta property=\"og:image:width\" content=\"720\" \/>\n\t<meta property=\"og:image:height\" content=\"554\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/webp\" \/>\n<meta name=\"author\" content=\"\u0639\u0628\u062f\u0647 \u0627\u0644\u0645\u0647\u062f\u064a\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u0643\u064f\u062a\u0628 \u0628\u0648\u0627\u0633\u0637\u0629\" \/>\n\t<meta name=\"twitter:data1\" content=\"\u0639\u0628\u062f\u0647 \u0627\u0644\u0645\u0647\u062f\u064a\" \/>\n\t<meta name=\"twitter:label2\" content=\"\u0648\u0642\u062a \u0627\u0644\u0642\u0631\u0627\u0621\u0629 \u0627\u0644\u0645\u064f\u0642\u062f\u0651\u0631\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 \u062f\u0642\u0627\u0626\u0642\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/indexeconomic.com\\\/?p=131687#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/indexeconomic.com\\\/?p=131687\"},\"author\":{\"name\":\"\u0639\u0628\u062f\u0647 \u0627\u0644\u0645\u0647\u062f\u064a\",\"@id\":\"https:\\\/\\\/indexeconomic.com\\\/#\\\/schema\\\/person\\\/ec72ed13059cd206a1153d37f4287a48\"},\"headline\":\"Wegovy\u00ae pill (oral semaglutide) recommended by CHMP for approval in the EU as the first oral GLP-1 representing the most efficacious oral obesity treatment in its class\",\"datePublished\":\"2026-06-06T15:07:37+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/indexeconomic.com\\\/?p=131687\"},\"wordCount\":442,\"commentCount\":0,\"image\":{\"@id\":\"https:\\\/\\\/indexeconomic.com\\\/?p=131687#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/indexeconomic.com\\\/wp-content\\\/uploads\\\/2026\\\/06\\\/02-1-18.webp\",\"articleSection\":[\"English News\"],\"inLanguage\":\"ar\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/indexeconomic.com\\\/?p=131687#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/indexeconomic.com\\\/?p=131687\",\"url\":\"https:\\\/\\\/indexeconomic.com\\\/?p=131687\",\"name\":\"Wegovy\u00ae pill (oral semaglutide) recommended by CHMP for approval in the EU as the first oral GLP-1 representing the most efficacious oral obesity treatment in its class - 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